Original Research

Perspectives on oral pre-exposure prophylaxis use amongst female sex workers in Harare, Zimbabwe

Tinashe Mudzviti, Anesu Dhliwayo, Byrone Chingombe, Bernard Ngara, Tsitsi G. Monera-Penduka, Charles C. Maponga, Gene D. Morse
Southern African Journal of HIV Medicine | Vol 21, No 1 | a1039 | DOI: https://doi.org/10.4102/sajhivmed.v21i1.1039 | © 2020 Tinashe Mudzviti, Anesu Dhliwayo, Byrone Chingombe, Bernard Ngara, Tsitsi G. Monera-Penduka, Charles C. Maponga, Gene D. Morse | This work is licensed under CC Attribution 4.0
Submitted: 22 October 2019 | Published: 19 February 2020

About the author(s)

Tinashe Mudzviti, School of Pharmacy, University of Zimbabwe, Harare, Zimbabwe; and, Newlands Clinic, Harare, Zimbabwe
Anesu Dhliwayo, School of Pharmacy, University of Zimbabwe, Harare, Zimbabwe
Byrone Chingombe, Population Services International, Harare, Zimbabwe
Bernard Ngara, Department of Community Medicine, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe
Tsitsi G. Monera-Penduka, School of Pharmacy, University of Zimbabwe, Harare, Zimbabwe
Charles C. Maponga, School of Pharmacy, College of Health Sciences, University of Zimbabwe, Harare; and, Population Services International, Harare, Zimbabwe; and, Center for Integrated Global Biomedical Sciences, University at Buffalo, New York,, United States
Gene D. Morse, Center for Integrated Global Biomedical Sciences, University at Buffalo, New York, United States; and, Translational Pharmacology Research Core, University at Buffalo, New York, United States

Abstract

Background: Pre-exposure prophylaxis (PrEP) could provide protection from human immunodeficiency virus (HIV) infection in sexually active persons at risk. Limited data are available in Zimbabwe with regard to the perceptions about PrEP amongst female sex workers (FSWs).

Objectives: The aim of this study was to evaluate the knowledge levels of oral PrEP and the likelihood of its use amongst FSWs.

Method: This was a cross-sectional study in the peri-urban areas of Harare, Zimbabwe. Human immunodeficiency virus-negative FSWs were interviewed to assess their awareness of and likelihood to use PrEP. The relative importance index was used to evaluate the levels of knowledge and the likelihood of, and barriers to, PrEP use. A set of 10 questions was designed and validated that evaluated participants’ understanding of PrEP. A bivariate logistic regression model was utilised to identify predictors of PrEP use.

Results: A total of 131 FSWs with a median age of 25 years (interquartile range: 21–31) participated in this study. Of the 71 (54%) FSWs who had heard about PrEP, 46 (35%) participants had adequate knowledge of its use. A total of 102 (78%) participants revealed that they would be willing to continuously use PrEP if it was provided free of cost. Increasing age of the participants was associated with an increase in the likelihood of using PrEP (r = 0.0033, p = 0.038). More knowledge about PrEP increased the likelihood of its use (r = 0.21, p = 0.0153). This likelihood increased amongst participants with an unprotected sexual intercourse encounter in the preceding 3 months (r = 0.0448, p = 0.026).

Conclusion: Knowledge of PrEP amongst FSWs was low. To increase the uptake of PrEP, there is a need to further sensitise FSWs about this intervention. Programmes should also promote awareness training in FSW subgroups that are less likely to use PrEP.


Keywords

female sex workers; HIV; pre-exposure prophylaxis; barriers; Truvada

Metrics

Total abstract views: 3714
Total article views: 4056

 

Crossref Citations

1. Utilization of HIV Pre-exposure Prophylaxis and Associated Factors Among Female Sex Workers in Bahir Dar City, North-West Ethiopia, Cross-sectional Study, 2022
Bezza Ademe, Eyob Bogale, Tadele Anagaw
International Journal of General Medicine  vol: Volume 16  first page: 6015  year: 2023  
doi: 10.2147/IJGM.S443477