Forum
Tuberculosis prevention in HIV-infected pregnant women in South Africa
Southern African Journal of HIV Medicine | Vol 13, No 4 | a113 |
DOI: https://doi.org/10.4102/sajhivmed.v13i4.113
| © 2012 C E Martin, V Black
| This work is licensed under CC Attribution 4.0
Submitted: 15 December 2012 | Published: 04 October 2012
Submitted: 15 December 2012 | Published: 04 October 2012
About the author(s)
C E Martin, WITS Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaV Black, WITS Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Abstract
The high burden of HIV and tuberculosis (TB) among pregnant women in South Africa contributes to a high maternal mortality rate. Isoniazid preventive therapy (IPT) is recommended for the prevention of active TB in HIV-infected individuals, including pregnant women. However, there are few data regarding IPT use in the latter, with concern regarding the concurrent use of IPT with nevirapine in pregnancy, as both treatments are hepatotoxic. The benefit and safety of IPT in HIV-infected pregnant women has not been established. We recommend a simplification of HIV and TB interventions by providing triple antiretroviral therapy to all HIV-infected pregnant women.
Keywords
No related keywords in the metadata.
Metrics
Total abstract views: 3954Total article views: 14196