Opinion Paper
How can we reduce the risk of mother-to-child transmission of HIV during invasive obstetric procedures?
Southern African Journal of HIV Medicine | Vol 12, No 3 | a179 |
DOI: https://doi.org/10.4102/sajhivmed.v12i3.179
| © 2011 C N Mnyani, E Nicolaou, E Bera, V Black, J C Hull, J A McIntyre
| This work is licensed under CC Attribution 4.0
Submitted: 15 December 2011 | Published: 30 September 2011
Submitted: 15 December 2011 | Published: 30 September 2011
About the author(s)
C N Mnyani, Anova Health Institute, South AfricaE Nicolaou, Maternal Fetal Medicine Centre, Morningside MediClnic, University of the Witwatersrand, Johannesburg, Department of Obstetrics and Gynaecology, Chris Hani Baragwanath Academic Hospital, Johannesburg
E Bera, Department of Obstetrics and Gynaecology, Rahima Moosa Mother and Child Hospital, University of the Witwatersrand, Johannesburg
V Black, Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg
J C Hull, Department of Obstetrics and Gynaecology, Chris Hani Baragwanath Academic Hospital, Johannesburg
J A McIntyre, Anova Health Institute, Johannesburg; Centre for Infectious Diseases Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town
Abstract
Antenatal invasive obstetric procedures may be diagnostic or therapeutic, and are performed at different stages of pregnancy for various indications. The commonest indication for an invasive procedure during pregnancy is for fetal karyotyping when a chromosomal abnormality or a genetic defect is suspected, either from the couple’s history or from ultrasound assessment of the fetus. Other less common but equally important indications may be diagnostic (fetoscopy, fetal tissue sampling, estimation of fetal haemoglobin) or therapeutic (aspiration of various fetal cavities, fetal blood transfusion and embryo reductions). In a high HIV prevalence setting like South Africa, a significant proportion of pregnant women in need of invasive procedures will be HIV-infected.
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