Original Research

The profile and frequency of known risk factors or comorbidities for deep vein thrombosis in an urban district hospital in KwaZulu-Natal

Damilola Awolesi, Mergan Naidoo, Mohammed H. Cassimijee
Southern African Journal of HIV Medicine | Vol 17, No 1 | a425 | DOI: https://doi.org/10.4102/sajhivmed.v17i1.425 | © 2016 Damilola Awolesi, Mergan Naidoo, Mohammed H. Cassimijee | This work is licensed under CC Attribution 4.0
Submitted: 22 September 2015 | Published: 13 May 2016

About the author(s)

Damilola Awolesi, Department of Family Medicine, University of KwaZulu-Natal, South Africa
Mergan Naidoo, Department of Family Medicine, University of KwaZulu-Natal, South Africa
Mohammed H. Cassimijee, Department of Family Medicine, University of KwaZulu-Natal, South Africa

Abstract

Background: Although deep vein thrombosis (DVT) is a preventable disease, it increases the morbidity and mortality in hospitalised, patients, resulting in considerable economic health impact. The identification and primary prevention of risk factors using risk assessment and stratification with subsequent anti-thrombotic prophylaxis in moderate- to severe-risk categories is the most rational means of reducing morbidity and mortality.

Aim and setting: The aim of the study was to describe the profile and frequency of known risk factors or comorbidities of hospitalised medical patients with ultrasound-diagnosed DVT in an urban district hospital in KwaZulu-Natal.

Methods: A retrospective review of clinical notes of all medical patients (age ≥ 13 years) admitted to the hospital with ultrasound-diagnosed DVT between July and December 2013.

Results: The median age was 40 years (interquartile range 32–60 years) and female preponderance was 72.84%. HIV and tuberculosis emerged as the prevalent risk factors, accounting for 51.85% and 35.80%, respectively. Other risk factors observed were recent hospitalisation (34.57%), smoking (25.93%), previous DVT (19.75%) and congestive cardiac failure (18.52%).

Conclusion: DVT in our study occurred predominantly in young female patients unlike previous studies where patients were generally older. Furthermore, HIV and tuberculosis were the two most common known risk factors or comorbidities observed. Clinicians should have a heightened awareness of venous thromboembolism in patients with either condition or where both conditions occur together and appropriate thromboprophylaxis should be administered.

Keywords: Deep Vein Thrombosis; risk factors; profile


Keywords

Deep Vein Thrombosis; risk factors; profile

Metrics

Total abstract views: 7402
Total article views: 13565

 

Crossref Citations

1. High incidence of undiagnosed deep vein thrombosis among hospitalized people living with HIV: a cross-sectional study
Robert Bizaleri Baluku, Faith Ameda, Eva Nabawanuka, Christine Sekaggya-Wiltshire
Thrombosis Journal  vol: 23  issue: 1  year: 2025  
doi: 10.1186/s12959-025-00743-7

2. Deep vein thrombosis as a public health priority: wHO’s agenda for Africa 2030
Emmanuel Ifeanyi Obeagu
Frontiers in Cardiovascular Medicine  vol: 13  year: 2026  
doi: 10.3389/fcvm.2026.1841390

3. Pregnancy Related Venous Thromboembolism-Associated with HIV Infection and Antiretroviral Therapy
Elise Schapkaitz, Barry F. Jacobson, Elena Libhaber
Seminars in Thrombosis and Hemostasis  vol: 49  issue: 04  first page: 355  year: 2023  
doi: 10.1055/s-0042-1754391

4. Incidence and Risk Factors for Postoperative Venous Thromboembolic Events in Patients Undergoing Cervical Spine Surgery
Annelise Bui, Nassim Lashkari, Blake Formanek, Jeffrey C. Wang, Zorica Buser, John C. Liu
Clinical Spine Surgery  vol: 34  issue: 8  first page: E458  year: 2021  
doi: 10.1097/BSD.0000000000001140

5. A Mechano-Chemical Computational Model of Deep Vein Thrombosis
Qudus Jimoh-Taiwo, Rashid Haffejee, Malebogo Ngoepe
Frontiers in Physics  vol: 10  year: 2022  
doi: 10.3389/fphy.2022.886193

6. Risk factors and HIV infection among patients diagnosed with deep vein thrombosis at a regional/tertiary hospital in Kimberley, South Africa
FK Mampuya, WJ Steinberg, JE Raubenheimer
South African Family Practice  vol: 60  issue: 4  first page: 107  year: 2018  
doi: 10.1080/20786190.2018.1432135

7. A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa
Lara Nicole Goldstein, Ming-Tung Wu
African Journal of Emergency Medicine  vol: 8  issue: 1  first page: 12  year: 2018  
doi: 10.1016/j.afjem.2017.08.006

8. The Genetics of Warfarin Dose–Response Variability in Africans: An Expert Perspective on Past, Present, and Future
Arinao Ndadza, Nicholas Ekow Thomford, Stanley Mukanganyama, Ambroise Wonkam, Mpiko Ntsekhe, Collet Dandara
OMICS: A Journal of Integrative Biology  vol: 23  issue: 3  first page: 152  year: 2019  
doi: 10.1089/omi.2019.0018

9. Evaluation of the modified Wells score in predicting venous thromboembolic disease in patients with tuberculosis or HIV in a South African setting
Tweedy Keokgale, Sarah A. Van Blydenstein, Ishmail S. Kalla
Southern African Journal of HIV Medicine  vol: 23  issue: 1  year: 2022  
doi: 10.4102/sajhivmed.v23i1.1349

10. Improving anticoagulation in sub‐Saharan Africa: What are the challenges and how can we overcome them?
Johannes P. Mouton, Marc Blockman, Christine Sekaggya‐Wiltshire, Jerome Semakula, Catriona Waitt, Munir Pirmohamed, Karen Cohen
British Journal of Clinical Pharmacology  vol: 87  issue: 8  first page: 3056  year: 2021  
doi: 10.1111/bcp.14768

11. Derangement of protein S and C4b-binding protein levels as acquired thrombophilia in HIV-infected adult Nigerians
Fatai O. Bello, Alani S. Akanmu, Titilope A. Adeyemo, Bukunmi M. Idowu, Prosper Okonkwo, Phyllis J. Kanki
Southern African Journal of HIV Medicine  vol: 22  issue: 1  year: 2021  
doi: 10.4102/sajhivmed.v22i1.1253

12. Management of active tuberculosis in adults with HIV
Graeme Meintjes, James C M Brust, James Nuttall, Gary Maartens
The Lancet HIV  vol: 6  issue: 7  first page: e463  year: 2019  
doi: 10.1016/S2352-3018(19)30154-7

13. Clinical Profile of Patients Admitted With Venous Thrombosis to a Tertiary Care Hospital in India
Bibin George, Sujeet Raina, Rajesh Sharma, Narvir S Chauhan, Krishna B Reddy
Cureus  year: 2026  
doi: 10.7759/cureus.102603

14. The Length of Hospital Stay of Patients with Venous Thromboembolism: A Cross-Sectional Study from Jordan
Haneen Amawi, Rasha M. Arabyat, Sayer Al-Azzam, Toqa AlZu’bi, Hamza Tayseer U’wais, Alaa M. Hammad, Ruba Amawi, Mohammad B. Nusair
Medicina  vol: 59  issue: 4  first page: 727  year: 2023  
doi: 10.3390/medicina59040727

15. To Study the Clinico-Radiological Profile of Patients of Pulmonary Tuberculosis with Deep Vein Thrombosis
Deepak Sharma, Prabhpreet Sethi, Anita Yadav
The International Journal of Mycobacteriology  vol: 10  issue: 1  first page: 26  year: 2021  
doi: 10.4103/ijmy.ijmy_203_20