Email this article 
Hide
Show all
Review Article
Human papillomavirus infection and disease in men: Impact of HIV
Submitted: 12 December 2013 | Published: 22 November 2013
About the author(s)
Sinead Delany-Moretlwe, Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa, South AfricaA Chikandiwa, Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa
J Gibbs, Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa; London School of Hygiene and Tropical Medicine, London, United Kingdom
Abstract
There is growing evidence of a significant burden of human papillomavirus (HPV) infection and associated disease in men. High rates of HPV infection have been observed in men from sub-Saharan Africa where HIV prevalence is high. HIV infection increases HPV prevalence, incidence and persistence and is strongly associated with the development of anogenital warts and anal, penile and head and neck cancers in men. Despite increasing access to antiretroviral therapy, there appears to be little benefit in preventing the development of these cancers in HIV-positive men, making prevention of infection a priority. New prevention options that are being introduced in many African countries include male circumcision and HPV vaccination. However, more data are needed on the burden of HPV disease in men before boys are included in HPV vaccination programmes.
Keywords
Metrics
Total abstract views: 4749Total article views: 10351
Crossref Citations
1. Strengthening anal cancer prevention in Abuja, Nigeria: Identifying barriers and potential strategies to improve training
Connor R. Volpi, John Chama, Megan E. Mansfield, Ruxton Adebiyi, Andrew Mitchell, Jumoke A. Aigoro, Yerima Jibrin Bawa, Kazeem E. Kolawole, Uchenna Ononaku, Paul Jibrin, Oluwole Olaomi, Francis Agbo, Soren M. Bentzen, Stephen E. Goldstone, Patrick Dakum, Joel M. Palefsky, Cheryl Knott, Sylvia Adebajo, Rebecca G. Nowak, Ejemai Eboreime
PLOS Global Public Health vol: 5 issue: 7 first page: e0004616 year: 2025
doi: 10.1371/journal.pgph.0004616
2. Oropharyngeal HPV infection: prevalence and sampling methods among HIV-infected men in South Africa
Admire Chikandiwa, Pedro T Pisa, Matthew F Chersich, Etienne E Muller, Philippe Mayaud, Sinead Delany-Moretlwe
International Journal of STD & AIDS vol: 29 issue: 8 first page: 776 year: 2018
doi: 10.1177/0956462418755882
3. Prevalent, persistent anal HPV infection and squamous intraepithelial lesions: Findings from a cohort of men living with HIV in South Africa
Admire Chikandiwa, Pedro. T. Pisa, Catherine Tamalet, Etienne. E. Muller, Pamela Michelow, Matthew. F. Chersich, Philippe Mayaud, Sinead Delany-Moretlwe, Graciela Andrei
PLOS ONE vol: 14 issue: 12 first page: e0225571 year: 2019
doi: 10.1371/journal.pone.0225571
4. Patterns and trends of HPV-related cancers other than cervix in South Africa from 1994–2013
Admire Chikandiwa, Pedro T. Pisa, Mazvita Sengayi, Elvira Singh, Sinead Delany-Moretlwe
Cancer Epidemiology vol: 58 first page: 121 year: 2019
doi: 10.1016/j.canep.2018.12.004
5. Incidence, Persistence, Clearance, and Correlates of Genital Human Papillomavirus Infection and Anogenital Warts in a Cohort of Men Living With Human Immunodeficiency Virus in South Africa
Admire Chikandiwa, Pedro T. Pisa, Etienne E. Muller, Catherine Tamalet, Philippe Mayaud, Matthew F. Chersich, Sinead Delany-Moretlwe
Sexually Transmitted Diseases vol: 46 issue: 5 first page: 347 year: 2019
doi: 10.1097/OLQ.0000000000000979