Guideline

Adult antiretroviral therapy guidelines 2017

Graeme Meintjes, Michelle A. Moorhouse, Sergio Carmona, Natasha Davies, Sipho Dlamini, Cloete van Vuuren, Thandekile Manzini, Moeketsi Mathe, Yunus Moosa, Jennifer Nash, Jeremy Nel, Yoliswa Pakade, Joana Woods, Gert van Zyl, Francesca Conradie, Francois Venter
Southern African Journal of HIV Medicine | Vol 18, No 1 | a776 | DOI: https://doi.org/10.4102/sajhivmed.v18i1.776 | © 2017 Graeme Meintjes, Michelle A. Moorhouse, Sergio Carmona, Natasha Davies, Sipho Dlamini, Cloete van Vuuren, Thandekile Manzini, Moeketsi Mathe, Yunus Moosa, Jennifer Nash, Jeremy Nel, Yoliswa Pakade, Joana Woods, Gert van Zyl, Francesca Conradie, Francois Venter | This work is licensed under CC Attribution 4.0
Submitted: 19 June 2017 | Published: 14 July 2017

About the author(s)

Graeme Meintjes, Southern African HIV Clinicians Society, South Africa
Michelle A. Moorhouse, Southern African HIV Clinicians Society, South Africa
Sergio Carmona, Southern African HIV Clinicians Society, South Africa
Natasha Davies, Southern African HIV Clinicians Society, South Africa
Sipho Dlamini, Southern African HIV Clinicians Society, South Africa
Cloete van Vuuren, Southern African HIV Clinicians Society, South Africa
Thandekile Manzini, Southern African HIV Clinicians Society, South Africa
Moeketsi Mathe, Southern African HIV Clinicians Society, South Africa
Yunus Moosa, Southern African HIV Clinicians Society, South Africa
Jennifer Nash, Southern African HIV Clinicians Society, South Africa
Jeremy Nel, Southern African HIV Clinicians Society, South Africa
Yoliswa Pakade, Southern African HIV Clinicians Society, South Africa
Joana Woods, Southern African HIV Clinicians Society, South Africa
Gert van Zyl, Southern African HIV Clinicians Society, South Africa
Francesca Conradie, Southern African HIV Clinicians Society, South Africa
Francois Venter, Southern African HIV Clinicians Society, South Africa

Abstract

These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in 2014 and the update on when to initiate antiretroviral therapy in 2015. Since the release of the previous guidelines, the scale-up of antiretroviral therapy (ART) in southern Africa has continued. New antiretroviral drugs have become available with improved efficacy, safety and robustness. The guidelines are intended for countries in the southern African region, which vary between lower and middle income.

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Southern African Journal of HIV Medicine  vol: 22  issue: 1  year: 2021  
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61. A comparative analysis of voluntary medical male circumcision before and during the COVID-19 pandemic in Gauteng province, South Africa
Cyril B. Fonka
South African Family Practice  vol: 67  issue: 1  year: 2025  
doi: 10.4102/safp.v67i1.6062

62. Association of predicted 10 years cardiovascular mortality risk with duration of HIV infection and antiretroviral therapy among HIV-infected individuals in Durban, South Africa
Olamide O. Todowede, Benn Sartorius, Nombulelo Magula, Aletta E. Schutte
Diabetology & Metabolic Syndrome  vol: 11  issue: 1  year: 2019  
doi: 10.1186/s13098-019-0502-2

63. Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and availability of integrase inhibitors in Cape Town, South Africa
Dominik Brado, Adetayo Emmanuel Obasa, George Mondinde Ikomey, Ruben Cloete, Kamalendra Singh, Susan Engelbrecht, Ujjwal Neogi, Graeme Brendon Jacobs
Scientific Reports  vol: 8  issue: 1  year: 2018  
doi: 10.1038/s41598-018-22914-5

64. Physiological effects of physical activity on neurocognitive function in people living with HIV : a systematic review of intervention and observational studies
M.C. Nweke, N. Mshunqane, N. Govender, O.A. Akinpelu
African Journal for Physical Activity and Health Sciences (AJPHES)  vol: 27  issue: 1  first page: 101  year: 2021  
doi: 10.37597/ajphes.2021.27.1.8

65. Rehabilitation of HIV-associated neurocognitive disorder: a systematic scoping review of available interventions
Martins Nweke, Mshunqane Nombeko, Nalini Govender, Aderonke O. Akineplu
Advances in Mental Health  vol: 20  issue: 3  first page: 200  year: 2022  
doi: 10.1080/18387357.2021.1981142

66. Aerobic Exercise in HIV-Associated Neurocognitive Disorders: Protocol for a Randomized Controlled Trial
Martins Nweke, Nombeko Mshunqane, Nalini Govender, Aderonke Akinpelu, Adesola Ogunniyi
JMIR Research Protocols  vol: 11  issue: 1  first page: e29230  year: 2022  
doi: 10.2196/29230

67. Good Functional Outcomes and Low Infection Rates in Total Hip Arthroplasty in HIV-Positive Patients, Provided There Is Strict Compliance With Highly Active Antiretroviral Therapy
Shahil Rajcoomar, Riona Rajcoomar, Michael Rafferty, Dick van der Jagt, Lipalo Mokete, Jurek R.T. Pietrzak
The Journal of Arthroplasty  vol: 36  issue: 2  first page: 593  year: 2021  
doi: 10.1016/j.arth.2020.08.021

68. Metabolic profiling of HIV infected individuals on an AZT-based antiretroviral treatment regimen reveals persistent oxidative stress
Lungile Sitole, Roxanne Fortuin, Fidele Tugizimana
Journal of Pharmaceutical and Biomedical Analysis  vol: 220  first page: 114986  year: 2022  
doi: 10.1016/j.jpba.2022.114986

69. Treatment advantage in HBV/HIV coinfection compared to HBV monoinfection in a South African cohort
Tongai G. Maponga, Anna L. McNaughton, Marije van Schalkwyk, Susan Hugo, Chikezie Nwankwo, Jantjie Taljaard, Jolynne Mokaya, David A. Smith, Cloete van Vuuren, Dominique Goedhals, Shiraaz Gabriel, Monique I. Andersson, Wolfgang Preiser, Christo van Rensburg, Philippa C. Matthews
Journal of Infection  vol: 81  issue: 1  first page: 121  year: 2020  
doi: 10.1016/j.jinf.2020.04.037

70. Sociodemographic and psychosocial predictors of longitudinal antiretroviral therapy (ART) adherence among first-time ART initiators in Cape Town, South Africa
Alissa Davis, Andrea Norcini Pala, Nadia Nguyen, Reuben N. Robbins, John Joska, Hetta Gouse, Claude A. Mellins, Landon Myer, Michelle Henry, Cheng Shiun Leu, Robert H. Remien
AIDS Care  vol: 33  issue: 11  first page: 1394  year: 2021  
doi: 10.1080/09540121.2020.1798336

71. HIV-1 drug resistance in adults and adolescents on protease inhibitor-based antiretroviral therapy in KwaZulu-Natal Province, South Africa
Benjamin Chimukangara, Richard J. Lessells, Benn Sartorius, Lilishia Gounder, Sontaga Manyana, Melendhran Pillay, Lavanya Singh, Jennifer Giandhari, Kerusha Govender, Reshmi Samuel, Nokukhanya Msomi, Kogieleum Naidoo, Tulio de Oliveira, Pravi Moodley, Raveen Parboosing
Journal of Global Antimicrobial Resistance  vol: 29  first page: 468  year: 2022  
doi: 10.1016/j.jgar.2021.10.023

72. CASCADE protocol: exploring current viral and host characteristics, measuring clinical and patient-reported outcomes, and understanding the lived experiences and needs of individuals with recently acquired HIV infection through a multicentre mixed-methods observational study in Europe and Canada
Elisa Ruiz-Burga, Shema Tariq, Giota Touloumi, John Gill, Emily Jay Nicholls, Caroline Sabin, Cristina Mussini, Laurence Meyer, Alain Volny Anne, Christina Carlander, Sophie Grabar, Inma Jarrin, Marc Van der Valk, Linda Wittkop, Bruno Spire, Nikos Pantazis, Fiona M Burns, Kholoud Porter
BMJ Open  vol: 13  issue: 5  first page: e070837  year: 2023  
doi: 10.1136/bmjopen-2022-070837

73. An Evaluation to Determine the Strongest CD4 Count Covariates during HIV Disease Progression in Women in South Africa
Partson Tinarwo, Temesgen Zewotir, Nonhlanhla Yende-Zuma, Nigel J. Garrett, Delia North
Infectious Diseases and Therapy  vol: 8  issue: 2  first page: 269  year: 2019  
doi: 10.1007/s40121-019-0235-4

74. Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals
Sinaye Ngcapu, Kristof Theys, Pieter Libin, Vincent Marconi, Henry Sunpath, Thumbi Ndung’u, Michelle Gordon
Viruses  vol: 9  issue: 11  first page: 330  year: 2017  
doi: 10.3390/v9110330

75. Factors associated with prognostic or treatment outcomes in HIV/AIDS patients with and without hypertension in Eswatini
Sabelo Bonginkosi Dlamini, Hans-Uwe Dahms, Ming-Tsang Wu
Scientific Reports  vol: 11  issue: 1  year: 2021  
doi: 10.1038/s41598-021-92185-0

76. Antiretroviral‐Induced Toxicity in Umbilical Cord Blood‐Derived Haematopoietic Stem/Progenitor Cells
Candice Laverne Hendricks, Andrea Ellero, Juanita Mellet, Voula Stivaktas, Michael Sean Pepper
Journal of Cellular and Molecular Medicine  vol: 29  issue: 8  year: 2025  
doi: 10.1111/jcmm.70557

77. Issues about periconception use of dolutegravir are reminiscent of early concerns about efavirenz
Vivian Black, Sheree R Schwartz
The Lancet HIV  vol: 5  issue: 12  first page: e732  year: 2018  
doi: 10.1016/S2352-3018(18)30249-2

78. Pleural tuberculosis: A concise clinical review
Jane A. Shaw, Elvis M. Irusen, Andreas H. Diacon, Coenraad F. Koegelenberg
The Clinical Respiratory Journal  vol: 12  issue: 5  first page: 1779  year: 2018  
doi: 10.1111/crj.12900

79. The seroprevalence of HIV in patients undergoing lower limb Total Joint Arthroplasty (TJA) in South Africa
Zia Maharaj, Jurek Rafal Tomasz Pietrzak, Nkhodiseni Sikhauli, Dick van de Jagt, Lipalo Mokete
SICOT-J  vol: 6  first page: 3  year: 2020  
doi: 10.1051/sicotj/2019042

80. Effects of Two Antiretroviral Drugs on the Crustacean Daphnia magna in River Water
Ntombikayise Mahaye, Ndeke Musee
Toxics  vol: 10  issue: 8  first page: 423  year: 2022  
doi: 10.3390/toxics10080423

81. Moving towards a person-centred HIV care cascade: An exploration of potential biases and errors in routine data in South Africa
David Etoori, Alison Wringe, Georges Reniers, Francesc Xavier Gomez-Olive, Brian Rice, Rashmi Josephine Rodrigues
PLOS Global Public Health  vol: 4  issue: 6  first page: e0002509  year: 2024  
doi: 10.1371/journal.pgph.0002509

82. Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection
Osaretin E. Asowata, Alveera Singh, Abigail Ngoepe, Nicholas Herbert, Rabiah Fardoos, Kavidha Reddy, Yenzekile Zungu, Faith Nene, Ntombifuthi Mthabela, Dirhona Ramjit, Farina Karim, Katya Govender, Thumbi Ndung’u, J. Zachary Porterfield, John H. Adamson, Fusi G. Madela, Vukani T. Manzini, Frank Anderson, Alasdair Leslie, Henrik N. Kløverpris
JCI Insight  vol: 6  issue: 22  year: 2021  
doi: 10.1172/jci.insight.146162

83. Impact of Lamivudine-Based Antiretroviral Treatment on Hepatitis B Viremia in HIV-Coinfected South Africans
Azwidowi Lukhwareni, Maemu Petronella Gededzha, Edina Amponsah-Dacosta, Jason T. Blackard, Rosemary J. Burnett, Selokela Gloria Selabe, Thanda Kyaw, M. Jeffrey Mphahlele
Viruses  vol: 12  issue: 6  first page: 634  year: 2020  
doi: 10.3390/v12060634

84. Analyses of HIV‐1 integrase gene sequences among treatment‐naive patients in the Eastern Cape, South Africa
Tennison Onoriode Digban, Benson Chucks Iweriebor, Larry Chikwelu Obi, Uchechuwku Nwodo, Anthony Ifeanyi Okoh
Journal of Medical Virology  vol: 92  issue: 8  first page: 1165  year: 2020  
doi: 10.1002/jmv.25661

85. Courier delivery of antiretroviral therapy: a cohort study of a South African private‐sector HIV programme
Yann Ruffieux, Naomi Folb, Anna Grimsrud, Michael Hislop, Liezl Dunn, Eliane Rohner, Anne Maria Namubiru, Chido Chinogurei, Morna Cornell, Mary‐Ann Davies, Matthias Egger, Gary Maartens, Andreas D. Haas
Journal of the International AIDS Society  vol: 27  issue: 9  year: 2024  
doi: 10.1002/jia2.26360

86. Electroanalytical sensors for antiretroviral drugs determination in pharmaceutical and biological samples: A review
Kefilwe V. Mokwebo, Samantha F. Douman, Onyinyechi V. Uhuo, Kaylin C. Januarie, Marlon Oranzie, Emmanuel I. Iwuoha
Journal of Electroanalytical Chemistry  vol: 920  first page: 116621  year: 2022  
doi: 10.1016/j.jelechem.2022.116621

87. Predictors of Treatment Adherence and Virological Failure Among People Living with HIV Receiving Antiretroviral Therapy in a South African Rural Community: A Sub-study of the ITREMA Randomised Clinical Trial
Siphamandla B. Gumede, Annemarie M. J. Wensing, Samanta T. Lalla-Edward, John B. F. de Wit, W. D. Francois Venter, Hugo A. Tempelman, Lucas E. Hermans
AIDS and Behavior  vol: 27  issue: 12  first page: 3863  year: 2023  
doi: 10.1007/s10461-023-04103-2

88. Timing, Dosage, and Adherence of Antiretroviral Therapy and Risk of Osteoporosis in Patients With Human Immunodeficiency Virus Infection in Taiwan: A Nested Case-Control Study
Mu-Lin Chiu, Wen-Miin Liang, Ju-Pi Li, Chi-Fung Cheng, Jian-Shiun Chiou, Mao-Wang Ho, Yang-Chang Wu, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Fuu-Jen Tsai, Ying-Ju Lin
Frontiers in Pharmacology  vol: 12  year: 2021  
doi: 10.3389/fphar.2021.631480

89. Aerobic exercise for HIV-associated neurocognitive disorders in individuals on antiretroviral therapy: A randomised controlled trial
Martins Nweke, Mshunqane Nombeko, Nalini Govender, Aderonke Akinpelu, Maryjane Ukwuoma, Adesola Ogunniyi
Clinical Rehabilitation  vol: 36  issue: 12  first page: 1601  year: 2022  
doi: 10.1177/02692155221114587

90. Magnitude of antiretroviral treatment failure and associated factors among adult HIV-positive patients in Harar public hospitals, Eastern Ethiopia
Rahel Feleke, Biftu Geda, Kedir Teji Roba, Fitsum Weldegebreal
SAGE Open Medicine  vol: 8  year: 2020  
doi: 10.1177/2050312120906076

91. Human Immunodeficiency Virus (HIV) Drug Resistance: A Global Narrative Review
Maureen Nkandu Phiri, Steward Mudenda
Journal of Biomedical Research & Environmental Sciences  vol: 2  issue: 9  first page: 857  year: 2021  
doi: 10.37871/jbres1323

92. Clinical significance of elevated liver transaminases in HIV-infected patients
Jia Cai, Maria Osikowicz, Giada Sebastiani
AIDS  vol: 33  issue: 8  first page: 1267  year: 2019  
doi: 10.1097/QAD.0000000000002233

93. Role of religious beliefs in adherence to antiretroviral therapy in the Cape Town metropole: a study protocol
Ivo Nchendia Azia, Shernaaz Carelse, Anam Nyembezi, Ferdinand C Mukumbang
BMJ Open  vol: 12  issue: 9  first page: e062464  year: 2022  
doi: 10.1136/bmjopen-2022-062464

94. Evaluation of the impact of delayed centrifugation on the diagnostic performance of serum creatinine as a baseline measure of renal function before antiretroviral treatment
Chemedzai E. Chikomba, Carolyn J. Padoa, Donald Tanyanyiwa
Southern African Journal of HIV Medicine  vol: 21  issue: 1  year: 2020  
doi: 10.4102/sajhivmed.v21i1.1056

95. An 8-year retrospective study of adult and paediatric Burkitt’s lymphoma at Tygerberg Hospital, South Africa
Ernest Musekwa, Zivanai C. Chapanduka, Fatima Bassa, Mariana Kruger
South African Journal of Oncology  vol: 4  year: 2020  
doi: 10.4102/sajo.v4i0.93

96. Subclinical tuberculosis among adults with HIV: clinical features and outcomes in a South African cohort
Kristina L. Bajema, Ingrid V. Bassett, Sharon M. Coleman, Douglas Ross, Kenneth A. Freedberg, Anna Wald, Paul K. Drain
BMC Infectious Diseases  vol: 19  issue: 1  year: 2019  
doi: 10.1186/s12879-018-3614-7

97. Shortened Tuberculosis Treatment for People with HIV in South Africa. A Model-based Evaluation and Cost-effectiveness Analysis
Krishna P. Reddy, C. Robert Horsburgh, Robin Wood, Naomi F. Fields, Michael P. Girouard, Sydney Costantini, Taige Hou, Kenneth A. Freedberg, Rochelle P. Walensky
Annals of the American Thoracic Society  vol: 17  issue: 2  first page: 202  year: 2020  
doi: 10.1513/AnnalsATS.201905-418OC

98. Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa
Adetayo Emmanuel Obasa, Anoop T. Ambikan, Soham Gupta, Ujjwal Neogi, Graeme Brendon Jacobs
BMC Infectious Diseases  vol: 21  issue: 1  year: 2021  
doi: 10.1186/s12879-021-05905-2

99. Late-onset efavirenz toxicity: A descriptive study from Pretoria, South Africa
Lyneshree Munsami, Clara M. Schutte, Maryke de Villiers, Juliane Hiesgen
Southern African Journal of HIV Medicine  vol: 24  issue: 1  year: 2023  
doi: 10.4102/sajhivmed.v24i1.1439

100. Adaption of an ongoing clinical trial to quickly respond to gaps in changing international recommendations: the experience of D 2 EFT
Emmanuelle Papot, Simone Jacoby, Dona Arlinda, Anchalee Avihingsanon, Iskandar Azwa, Margaret Borok, Dannae Brown, Mohamed Cissé, Sounkalo Dao, Nnakelu Eriobu, Richard Kaplan, Muhammad Karyana, Nagalingeswaran Kumarasamy, Johnnie Lee, Marcelo H. Losso, Gail V. Matthews, Leonardo Perelis, Carmen Perez-Casas, Kiat Ruxrungtham, Melynda Watkins, H. Clifford Lane, Anthony Kelleher, Matthew Law, Mark N. Polizzotto
HIV Research & Clinical Practice  vol: 23  issue: 1  first page: 37  year: 2022  
doi: 10.1080/25787489.2022.2103572

101. An audit of HIV-infected Patients Admitted to Helen Joseph Hospital in Johannesburg, South Africa
Gregory Yudelowitz, Prudence Ive, Mathew Fox
Wits Journal of Clinical Medicine  vol: 3  issue: 3  year: 2021  
doi: 10.18772/26180197.2021.v3n3a6

102. Important pharmacogenomic aspects in the management of HIV/AIDS
A Marais, E Osuch, V Steenkamp, L Ledwaba
South African Family Practice  vol: 61  issue: sup1  first page: S15  year: 2019  
doi: 10.1080/20786190.2019.1610233

103. Retention on ART and viral suppression among patients in alternative models of differentiated HIV service delivery in KwaZulu-Natal, South Africa
Altynay Shigayeva, Ntombi Gcwensa, Celiwe Dlamini Ndlovu, Nosicelo Ntumase, Scelinhlanhla Sabela, Liesbet Ohler, Laura Trivino-Duran, Ellie Ford Kamara, Khanyo Hlophe, Petros Isaakidis, Gilles Van Cutsem, Hannah Hogan Leslie
PLOS Global Public Health  vol: 2  issue: 12  first page: e0000336  year: 2022  
doi: 10.1371/journal.pgph.0000336

104. Excess mortality associated with mental illness in people living with HIV in Cape Town, South Africa: a cohort study using linked electronic health records
Andreas D Haas, Yann Ruffieux, Leigh Luella van den Heuvel, Crick Lund, Andrew Boulle, Jonathan Euvrard, Catherine Orrell, Hans W Prozesky, Nicki Tiffin, Kathryn L Lovero, Mpho Tlali, Mary-Ann Davies, Milton L Wainberg
The Lancet Global Health  vol: 8  issue: 10  first page: e1326  year: 2020  
doi: 10.1016/S2214-109X(20)30279-5

105. Assessing the potential for nevirapine removal and its ecotoxicological effects on Coelastrella tenuitheca and Tetradesmus obliquus in aqueous environment
Karen Reddy, Nirmal Renuka, Sheena Kumari, Sachitra Kumar Ratha, Brenda Moodley, Kriveshin Pillay, Faizal Bux
Environmental Pollution  vol: 317  first page: 120736  year: 2023  
doi: 10.1016/j.envpol.2022.120736

106. Switching at Low HIV-1 RNA into Fixed Dose Combinations: TDF/FTC/RPV is non-inferior to TDF/FTC/EFV in first-line suppressed patients living with HIV
Paula Munderi, Edwin Were, Anchalee Avihingsanon, Pascale A.M. Mbida, Lerato Mohapi, Samba B. Moussa, Marjolein Jansen, Ceyhun Bicer, Perry Mohammed, Yvon van Delft
Southern African Journal of HIV Medicine  vol: 20  issue: 1  year: 2019  
doi: 10.4102/sajhivmed.v20i1.949

107. Prevalence and correlates of depressive symptoms among adults living with HIV in rural Kilifi, Kenya
Moses K. Nyongesa, Paul Mwangi, Stanley W. Wanjala, Agnes M. Mutua, Charles R. J. C. Newton, Amina Abubakar
BMC Psychiatry  vol: 19  issue: 1  year: 2019  
doi: 10.1186/s12888-019-2339-5

108. The clinical and demographic profile of women living with HIV admitted to the acute unit at Stikland Psychiatric Hospital
Jean-Marie le Roux, Lina Groenewald, Karis Moxley, Liezl Koen
Southern African Journal of HIV Medicine  vol: 22  issue: 1  year: 2021  
doi: 10.4102/sajhivmed.v22i1.1159

109. The treatment gap for mental disorders in adults enrolled in HIV treatment programmes in South Africa: a cohort study using linked electronic health records
Y. Ruffieux, O. Efthimiou, L. L. Van den Heuvel, J. A. Joska, M. Cornell, S. Seedat, J. P. Mouton, H. Prozesky, C. Lund, N. Maxwell, M. Tlali, C. Orrell, M.-A. Davies, G. Maartens, A. D. Haas
Epidemiology and Psychiatric Sciences  vol: 30  year: 2021  
doi: 10.1017/S2045796021000196

110. Childhood trauma interacts with ApoE to influence neurocognitive function in women living with HIV
Jacqueline S. Womersley, Georgina Spies, Soraya Seedat, Sian M. J. Hemmings
Journal of NeuroVirology  vol: 25  issue: 2  first page: 183  year: 2019  
doi: 10.1007/s13365-018-0700-y

111. Quantifying the HIV treatment cascade in a South African health sub‐district by gender: retrospective cohort study
Mark N. Lurie, Kipruto Kirwa, Julia Callaway, Morna Cornell, Andrew Boulle, Angela M. Bengtson, Mariette Smith, Natalie Leon, Christopher Colvin
Tropical Medicine & International Health  vol: 25  issue: 2  first page: 186  year: 2020  
doi: 10.1111/tmi.13334

112. Seizures Causing Simultaneous Bilateral Neck of Femur Fractures
Dane Gary Maimin, Livan Meneses-Turino
Case Reports in Orthopedics  vol: 2019  first page: 1  year: 2019  
doi: 10.1155/2019/4570578

113. Drug Resistance Among Adolescents and Young Adults with Virologic Failure of First-Line Antiretroviral Therapy and Response to Second-Line Treatment
Vinie Kouamou, Bhavini Varyani, Tinei Shamu, Tichaona Mapangisana, Cleophas Chimbetete, Tinashe Mudzviti, Justen Manasa, David Katzenstein
AIDS Research and Human Retroviruses  vol: 36  issue: 7  first page: 566  year: 2020  
doi: 10.1089/aid.2019.0232

114. Evaluation of the HIV-1 Polymerase Gene Sequence Diversity for Prediction of Recent HIV-1 Infections Using Shannon Entropy Analysis
Paballo Nkone, Shayne Loubser, Thomas C. Quinn, Andrew D. Redd, Oliver Laeyendecker, Caroline T. Tiemessen, Simnikiwe H. Mayaphi
Viruses  vol: 14  issue: 7  first page: 1587  year: 2022  
doi: 10.3390/v14071587

115. Clinico-pathological characteristics among South African women with breast cancer receiving anti-retroviral therapy for HIV
Boitumelo Phakathi, Herbert Cubasch, Sarah Nietz, Caroline Dickens, Therese Dix-Peek, Maureen Joffe, Alfred I. Neugut, Judith Jacobson, Raquel Duarte, Paul Ruff
The Breast  vol: 43  first page: 123  year: 2019  
doi: 10.1016/j.breast.2018.12.005

116. Opinions of doctors working in South African critical care units regarding unconsented testing and empirical treatment of HIV-positive patients in ICU
AM Carpenter, AK Asghar, JN Mudali, MC Reade, R Wise
Southern African Journal of Anaesthesia and Analgesia  vol: 26  issue: 1  first page: 38  year: 2020  
doi: 10.36303/SAJAA.2020.26.1.2291

117. Postpartum obesity and weight gain among human immunodeficiency virus‐infected and human immunodeficiency virus‐uninfected women in South Africa
Angela M. Bengtson, Tamsin K. Phillips, Stanzi M. le Roux, Kirsty Brittain, Allison Buba, Elaine J. Abrams, Landon Myer
Maternal & Child Nutrition  vol: 16  issue: 3  year: 2020  
doi: 10.1111/mcn.12949

118. In the South African setting, HIV-associated Burkitt lymphoma is associated with frequent leukaemic presentation, complex cytogenetic karyotypes, and adverse clinical outcomes
Jessica Opie, Katherine Antel, Ania Koller, Nicolas Novitzky
Annals of Hematology  vol: 99  issue: 3  first page: 571  year: 2020  
doi: 10.1007/s00277-020-03908-8

119. ERAS perioperative management measures in total hip replacement in HIV-positive patients with osteonecrosis of the femoral head
Shengtao Li, Bo Liu, Rui Ma, Kangpeng Li, Qiang Zhang
Journal of Orthopaedic Surgery and Research  vol: 19  issue: 1  year: 2024  
doi: 10.1186/s13018-024-05255-0

120. Indications and diagnostic value of bone marrow examination in HIV-positive individuals: A 3-year review at Tygerberg Hospital
Ibtisam Abdullah, Nadhiya Subramony, Ernest Musekwa, Erica-Mari Nell, Fatima Alzanad, Carissa Chetty, Ethan Gantana, Robert K. Lohlun, Wardah Cerfontein, Bridget Cochrane, Zivanai C. Chapanduka
Southern African Journal of Infectious Diseases  vol: 36  issue: 1  year: 2021  
doi: 10.4102/sajid.v36i1.273

121. Pharmacogenetics of Antiretroviral Drug Response and Pharmacokinetic Variations in Indigenous South African Populations
Kevin S. O'Connell, Marelize Swart, Nathaniel W. McGregor, Collet Dandara, Louise Warnich
OMICS: A Journal of Integrative Biology  vol: 22  issue: 9  first page: 589  year: 2018  
doi: 10.1089/omi.2018.0117

122. Neurocognitive improvement in HIV-positive patients treated with dolutegravir-based regimens
Janine Rodrigues, Karishma Lowton
South African Journal of Psychiatry  vol: 29  year: 2023  
doi: 10.4102/sajpsychiatry.v29i0.2071

123. Same-day antiretroviral therapy initiation for HIV-infected adults in South Africa: Analysis of routine data
Rivka R. Lilian, Kate Rees, James A. McIntyre, Helen E. Struthers, Remco P. H. Peters, Marcel Yotebieng
PLOS ONE  vol: 15  issue: 1  first page: e0227572  year: 2020  
doi: 10.1371/journal.pone.0227572

124. Motivating people living with HIV to initiate antiretroviral treatment outside national guidelines in three clinics in the HPTN 071 (PopART) trial, South Africa
Constance Mubekapi-Musadaidzwa, Dillon Wademan, Neshaan Peton, Portia Hendricks, Gabriela Carolus, Rheiner Mbaezue, Karen F Kelley, James Kruger, Karen Jennings, Nelis Grobbelaar, Francoise Louis, Nulda Beyers, Helen Ayles, Sarah Fidler, Richard Hayes, Peter Bock, Graeme Hoddinott
African Journal of AIDS Research  vol: 20  issue: 1  first page: 32  year: 2021  
doi: 10.2989/16085906.2020.1854795

125. Current and Future Therapeutic Strategies for Lentiviral Eradication from Macrophage Reservoirs
Tiffany A. Peterson, Andrew G. MacLean
Journal of Neuroimmune Pharmacology  vol: 14  issue: 1  first page: 68  year: 2019  
doi: 10.1007/s11481-018-9814-5

126. Antiretroviral therapy uptake and predictors of virological failure in patients with HIV receiving first-line and second-line regimens in Johannesburg, South Africa: a retrospective cohort data analysis
Siphamandla Bonga Gumede, Francois Venter, John de Wit, Annemarie Wensing, Samanta Tresha Lalla-Edward
BMJ Open  vol: 12  issue: 4  first page: e054019  year: 2022  
doi: 10.1136/bmjopen-2021-054019

127. Drug Resistance Mutations Against Protease, Reverse Transcriptase and Integrase Inhibitors in People Living With HIV-1 Receiving Boosted Protease Inhibitors in South Africa
Adetayo Emmanuel Obasa, Sello Given Mikasi, Dominik Brado, Ruben Cloete, Kamlendra Singh, Ujjwal Neogi, Graeme Brendon Jacobs
Frontiers in Microbiology  vol: 11  year: 2020  
doi: 10.3389/fmicb.2020.00438

128. Empowering Lay-Counsellors with Technology: Masivukeni, a Standardized Multimedia Counselling Support Tool to Deliver ART Counselling
H. Gouse, R. N. Robbins, C. A. Mellins, A. Kingon, J. Rowe, M. Henry, R. H. Remien, A. Pearson, F. Victor, J. A. Joska
AIDS and Behavior  vol: 22  issue: 10  first page: 3345  year: 2018  
doi: 10.1007/s10461-018-2145-y

129. Why adult patients on antiretroviral therapy miss clinical appointments in rural villages of Limpopo Province, South Africa: An exploratory study
Mygirl P. Lowane, Rachel T. Lebese
Health SA Gesondheid  vol: 27  year: 2022  
doi: 10.4102/hsag.v27i0.1989

130. Toxicological evaluation of antiretroviral Tenofovir Disoproxil Fumarate on the mollusk Biomphalaria glabrata and its hemocytes
Gabriel Souza-Silva, Clessius Ribeiro Souza, Cíntia Aparecida de Jesus Pereira, Walter dos Santos Lima, Marcos Paulo Gomes Mol, Micheline Rosa Silveira
Science of The Total Environment  vol: 891  first page: 164484  year: 2023  
doi: 10.1016/j.scitotenv.2023.164484

131. Molecular Genetics and the Incidence of Transmitted Drug Resistance Among Pre-Treatment HIV-1 Infected Patients in the Eastern Cape, South Africa
Tennison Onoriode Digban, Benson Chucks Iweriebor, Larry Chikwelu Obi, Uchechuwku Nwodo, Anthony Ifeanyi Okoh
Current HIV Research  vol: 17  issue: 5  first page: 335  year: 2019  
doi: 10.2174/1570162X17666191004093433

132. Study protocol for a phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous meningitis [LASER-TBM]
Angharad G. Davis, Sean Wasserman, Mpumi Maxebengula, Cari Stek, Marise Bremer, Remy Daroowala, Saalikha Aziz, Rene Goliath, Stephani Stegmann, Sonya Koekemoer, Amanda Jackson, Louise Lai Sai, Yakub Kadernani, Thandi Sihoyiya, C.Jason Liang, Lori Dodd, Paolo Denti, Thomas Crede, Jonathan Naude, Patryk Szymanski, Yakoob Vallie, Ismail Banderker, Shiraz Moosa, Peter Raubenheimer, Rachel P.J. Lai, John Joska, Sam Nightingale, Anna Dreyer, Gerda Wahl, Curtis Offiah, Isak Vorster, Sally Candy, Frances Robertson, Ernesta Meintjes, Gary Maartens, John Black, Graeme Meintjes, Robert J. Wilkinson
Wellcome Open Research  vol: 6  first page: 136  year: 2021  
doi: 10.12688/wellcomeopenres.16783.1

133. The association between HIV tri-therapy with the development of Type-2 Diabetes Mellitus in a rural South African District: A case-control study
Nokwanda E. Bam, Sikhumbuzo A. Mabunda, Jafta Ntsaba, Teke Apalata, Sibusiso C. Nomatshila, Wezile Chitha, Giordano Madeddu
PLOS ONE  vol: 15  issue: 12  first page: e0244067  year: 2020  
doi: 10.1371/journal.pone.0244067

134. The effect of HIV infection on glycaemia and renal function in type 2 diabetic patients
Siyabonga P. Khoza, Nigel J. Crowther, Sindeep Bhana, Wei Wang
PLOS ONE  vol: 13  issue: 6  first page: e0199946  year: 2018  
doi: 10.1371/journal.pone.0199946

135. Movement is Life—Optimizing Patient Access to Total Joint Arthroplasty: HIV and Hepatitis C Disparities
Daniel H. Wiznia, Randall C. Morgan, David Gibson
Journal of the American Academy of Orthopaedic Surgeons  vol: 30  issue: 21  first page: 1011  year: 2022  
doi: 10.5435/JAAOS-D-21-00427

136. Combination Antiretroviral Therapy (cART) in Diabetes Exacerbates Diabetogenic Effects on Hippocampal Microstructure, Neurogenesis and Cytokine Perturbation in Male Sprague Dawley Rats
Jaclyn Asouzu Johnson, Robert Ndou, Ejikeme Felix Mbajiorgu
Diagnostics  vol: 12  issue: 4  first page: 905  year: 2022  
doi: 10.3390/diagnostics12040905

137. The spectrum of electrolyte abnormalities in black African people living with human immunodeficiency virus and diabetes mellitus at Edendale Hospital, Pietermaritzburg, South Africa
Preyanka Pillay, Somasundram Pillay, Nobuhle Mchunu
Southern African Journal of HIV Medicine  vol: 21  issue: 1  year: 2020  
doi: 10.4102/sajhivmed.v21i1.1095

138. Survival of south african women with breast cancer receiving anti-retroviral therapy for HIV
Boitumelo Phakathi, Sarah Nietz, Herbert Cubasch, Caroline Dickens, Therese Dix-Peek, Maureen Joffe, Alfred I. Neugut, Judith Jacobson, Raquel Duarte, Paul Ruff
The Breast  vol: 59  first page: 27  year: 2021  
doi: 10.1016/j.breast.2021.05.014

139. Mental health, substance use and viral suppression in adolescents receiving ART at a paediatric HIV clinic in South Africa
Andreas D Haas, Karl‐Günter Technau, Shenaaz Pahad, Kate Braithwaite, Mampho Madzivhandila, Gillian Sorour, Shobna Sawry, Nicola Maxwell, Per von Groote, Mpho Tlali, Mary‐Ann Davies, Matthias Egger
Journal of the International AIDS Society  vol: 23  issue: 12  year: 2020  
doi: 10.1002/jia2.25644