Case Report

HIV sero-conversion during late pregnancy – when to retest

Emma Kalk, Amy Slogrove, David P Speert, Julie A Bettinger, Mark F Cotton, Monika Esser
Southern African Journal of HIV Medicine | Vol 14, No 2 | a84 | DOI: https://doi.org/10.4102/sajhivmed.v14i2.84 | © 2013 Emma Kalk, Amy Slogrove, David P Speert, Julie A Bettinger, Mark F Cotton, Monika Esser | This work is licensed under CC Attribution 4.0
Submitted: 12 December 2013 | Published: 04 June 2013

About the author(s)

Emma Kalk, Children’s Infectious Diseases Research Unit (KIDCRU), Department of Paediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa, South Africa
Amy Slogrove, Children’s Infectious Diseases Research Unit (KIDCRU), Department of Paediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa; Department of Pediatrics, University of British Columbia, Canada, South Africa
David P Speert, Department of Pediatrics, University of British Columbia, Canada, Canada
Julie A Bettinger, Vaccine Evaluation Center, British Columbia Children’s Hospital and University of British Columbia, Canada, Canada
Mark F Cotton, Children’s Infectious Diseases Research Unit (KIDCRU), Department of Paediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa, South Africa
Monika Esser, National Health Laboratory Service and Department of Pathology (Immunology), Stellenbosch University, Stellenbosch, South Africa, South Africa


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Abstract

The South African National Prevention of Mother-to-Child Transmission of HIV programme has resulted in significant reductions in vertical transmission, but new infant HIV infections continue to occur. We present two cases of HIV seroconversion during late pregnancy, demonstrating the limitations of the current programme. These could be mitigated by expanding the programme to include maternal testing at delivery and at immunisation clinic visits as we pursue the elimination of mother-to-child transmission.


Keywords

HIV; PMTCT; HIV seroconversion

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