Case Report
An interesting case of HSV pneumonia and PCP co-infection in a patient with AIDS: A diagnostic and management challenge
Submitted: 24 June 2019 | Published: 23 March 2009
About the author(s)
Mohammed Mitha, University of KwaZulu-Natal, Durban, and National Health Laboratory Service, South AfricaKriban Reddy, University of KwaZulu-Natal, South Africa
Raveen Parboosing, University of KwaZulu-Natal, Durban, and National Health Laboratory Service, South Africa
Yacoob Coovadia, University of KwaZulu-Natal, Durban, and National Health Laboratory Service, South Africa
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PDF (1MB)Abstract
The advent of HIV and AIDS has brought about many diagnostic and management challenges regarding multiple opportunistic infections. Pneumocystis jirovecii pneumonia (PCP) is a common presentation in patients with AIDS who are not on prophylaxis or highly active antiretroviral therapy (HAART). Herpes simplex 1 virus (HSV-1) is a ubiquitous virus that mainly causes benign disease during primary infection. However, it is known to cause severe pneumonia and disseminated disease in the immunocompromised.1 We present a case of HSV-1 pneumonitis and PCP co-infection in an HIV-positive patient with respiratory failure. To the best of our knowledge, based on Pubmed and Google Scholar searches, this is the first case to be reported in the English language literature.
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