Review Article

Hepatitis B co-infection in HIV-infected patients receiving antiretroviral therapy at the TC Newman Anti Retroviral Treatment Clinic in Paarl, Western Cape

Jeanmari King, Dirk T. Hagemeister
Southern African Journal of HIV Medicine | Vol 17, No 1 | a336 | DOI: | © 2016 Jeanmari King, Dirk T. Hagemeister | This work is licensed under CC Attribution 4.0
Submitted: 07 January 2015 | Published: 20 May 2016

About the author(s)

Jeanmari King, Division of Family Medicine and Primary Care, Stellenbosch University, South Africa; District Health Services, Western Cape Department of Health, South Africa
Dirk T. Hagemeister, Department of Family Medicine, University of the Free State, South Africa; Universitas Academic Hospital, Bloemfontein, South Africa


Background: Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) co-infection in South Africa is estimated to be between 5% and 23%; however, only limited evidence is available. Co-infection increases the risk of chronification of HBV, liver cirrhosis and death.

Objective: To assess the HBV and/or HIV co-infection rate amongst the adult antiretroviral treatment cohort at the TC Newman ART Clinic in Paarl, Western Cape.

Methods: In a retrospective, cross-sectional study, the routine hepatitis B surface antigen screening results for all adult HIV patients who were started on antiretroviral treatment over a period of 19 months were collected and analysed for gender, CD4 count and age.

Results: Amongst the 498 participants (60% female participants), the Hepatitis B surface Antigen positivity rate was 7.6%. Male gender, age between 50 and 59 years and a low CD4 count were correlated with higher rates.

Conclusion: Useful insight could be obtained by analysing routine data. The prevalence of almost 8% confirms the need for testing of HIV-positive patients for hepatitis B.

Keywords: hepatitis B; prevalence; HIV-infected; adults; co-infection


hepatitis B; prevalence; HIV-infected; adults; co-infection


Total abstract views: 3690
Total article views: 10914


Crossref Citations

1. Prevalence and characteristics of hepatitis B and D virus infections among HIV-positive individuals in Southwestern Nigeria
Oluyinka Oladele Opaleye, Olusola Anuoluwapo Akanbi, Folakemi Abiodun Osundare, Bo Wang, Olufisayo Adesina, Adeolu Sunday Oluremi, Sola Thomas Sunday, Abiodun Akeem Akindele, Patrycja Klink, C. Thomas Bock
Virology Journal  vol: 18  issue: 1  year: 2021  
doi: 10.1186/s12985-021-01493-4