Review Article

Hepatitis B co-infection in HIV-infected patients receiving antiretroviral therapy at the TC Newman Anti Retroviral Treatment Clinic in Paarl, Western Cape

Jeanmari King, Dirk T. Hagemeister
Southern African Journal of HIV Medicine | Vol 17, No 1 | a336 | DOI: https://doi.org/10.4102/sajhivmed.v17i1.336 | © 2016 Jeanmari King, Dirk T. Hagemeister | This work is licensed under CC Attribution 4.0
Submitted: 07 January 2015 | Published: 20 May 2016

About the author(s)

Jeanmari King, Division of Family Medicine and Primary Care, Stellenbosch University, South Africa; District Health Services, Western Cape Department of Health, South Africa
Dirk T. Hagemeister, Department of Family Medicine, University of the Free State, South Africa; Universitas Academic Hospital, Bloemfontein, South Africa


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Abstract

Background: Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) co-infection in South Africa is estimated to be between 5% and 23%; however, only limited evidence is available. Co-infection increases the risk of chronification of HBV, liver cirrhosis and death.

Objective: To assess the HBV and/or HIV co-infection rate amongst the adult antiretroviral treatment cohort at the TC Newman ART Clinic in Paarl, Western Cape.

Methods: In a retrospective, cross-sectional study, the routine hepatitis B surface antigen screening results for all adult HIV patients who were started on antiretroviral treatment over a period of 19 months were collected and analysed for gender, CD4 count and age.

Results: Amongst the 498 participants (60% female participants), the Hepatitis B surface Antigen positivity rate was 7.6%. Male gender, age between 50 and 59 years and a low CD4 count were correlated with higher rates.

Conclusion: Useful insight could be obtained by analysing routine data. The prevalence of almost 8% confirms the need for testing of HIV-positive patients for hepatitis B.

Keywords: hepatitis B; prevalence; HIV-infected; adults; co-infection


Keywords

hepatitis B; prevalence; HIV-infected; adults; co-infection

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